The gun is a classic symbol of rebellion, and the wild nature of the individual who gets a tattoo of this subject. It can also be understood as a symbol of personal freedom, independence, and a person who is able to solve the problems by their own efforts.
The most common location for a gun tattoo is to the side (where you would take a real gun) maybe doubling the subject on both sides wrapped in a holster, typical of the old west. For women it can be very sexy symbol when supported by a garter that surrounds the thigh as it gives a touch of danger and sensuality.